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Supplementary material The Supplementary material for this article can be found online at: References 1

Specifically, the FDA requests comments, including supporting data and research, regarding whether and to what extent this proposed rule would result in an increase in illicit trade in [normal nicotine content] cigarettes and certain other combusted tobacco products covered by the proposed nicotine product standard and how any such increase could impact public health

Smoking heavily disrupts lung function and lead to severe complications, including cardiovascular and respiratory disorders

Cardiovasc Res 114(10):13101312 Munzel T, Hahad O, Daiber A (2019) Double hazard of smoking and alcohol on vascular function in adolescents

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